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A pre-blended GHRH-analog plus selective ghrelin-receptor agonist. Co-lyophilized for synergistic-pulse GH-axis research protocols.
CJC-1295 / Ipamorelin pairs a 30-residue GHRH(1-29) analog with a 5-residue selective growth-hormone secretagogue (ghrelin-receptor agonist). The two mechanisms are studied in parallel for synergistic pulsatile GH release in cell-culture and rodent models.
Each component meets ≥ 99% HPLC purity independently before co-lyophilization. Vials are sealed under nitrogen and shipped cold-chain at −20 °C from our Kelowna facility.
Synergistic GHRH-R + GHS-R activation studies, pituitary GH-secretion potentiation assays, and comparative pulsatile-release pharmacokinetics versus CJC-1295 or Ipamorelin alone.
Sold for laboratory research only. This material is not a drug, food, or cosmetic and is not intended for diagnostic, therapeutic, or recreational use.
| Parameter | Value |
|---|---|
| Sequence | CJC-1295 (no DAC) + Ipamorelin |
| Molecular formula | Pre-blend |
| Molecular weight | Mixed (3367.93 + 711.86 g/mol) |
| CAS number | Mixed (863288-34-0 / 170851-70-4) |
| Length | Pre-blend (30 + 5 residues) |
| Test | Specification |
|---|---|
| HPLC purity | ≥ 99.0% (lot LM-2615: ≥ 99.0% per component) |
| Mass confirmation | ESI-MS within 0.5 Da |
| Net peptide content | ≥ 80% by AAA |
| Endotoxin | < 0.5 EU/mg (LAL) |
| Bioburden | < 10 CFU/g |
| Residual TFA | < 1.0% |
Manufactured 04 Mar 2026 · Released 11 Mar 2026 · Tested by Lumera QC, Kelowna BC. Retain samples held under storage spec for five years from release date.
| Method | Result |
|---|---|
| RP-HPLC at 220 nm | ≥ 99.0% per component main peak |
| ESI-MS (positive) | Two peaks: 3367.9 + 711.9 Da |
| Amino acid analysis | 82.1% net peptide |
| LAL endotoxin | < 0.05 EU/mg |
| Karl Fischer (water) | 2.8% w/w |
Allow vial to reach room temperature before opening (≥ 20 minutes). Reconstitute with 1.0–2.5 mL of sterile bacteriostatic water (0.9% benzyl alcohol). Inject solvent slowly down the inner wall of the vial; do not direct stream onto the lyophilized cake.
Swirl gently for 30 seconds. Do not vortex. Allow to dissolve for 5 minutes; clarity should be complete with no visible particulates.
Reconstituted solution is stable for 28 days at 2–8 °C in original vial. For longer storage, aliquot into low-binding tubes and hold at −80 °C; avoid repeated freeze-thaw cycles. Discard if turbidity, color change, or particulate matter is observed.
Raun K et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139(5):552–561.
Teichman SL et al. Prolonged stimulation of GH/IGF-I by CJC-1295. J Clin Endocrinol Metab. 2006;91(3):799–805.
Veldhuis JD, Bowers CY. Integrating GHRH agonism and ghrelin-receptor agonism. Endocrine. 2010;38(1):1–16.
CJC-1295 / Ipamorelin reference standard, ≥99% (HPLC), Lumera Labs Inc., Cat. No. LUM-CJCIPA-10, Lot 26-A031.